IMPORTANT RISK INFORMATION
Do not use CANASA if you are:
Before using CANASA, tell your healthcare provider if you:
have a history of allergic reaction to the medicine sulfasalazine (Azulfidine).
have kidney problems.
have ever had inflammation of the sac around your heart (pericarditis).
have liver problems.
have any other medical conditions.
are pregnant or plan to become pregnant. It is not known if CANASA can harm your
are breastfeeding or plan to breastfeed. CANASA can pass into your breast milk.
Talk to your healthcare provider about the best way to feed your baby if you use CANASA.
Tell your healthcare provider about all the medicines you take, including prescription and
over-the-counter medicines, vitamins, and herbal supplements. Taking CANASA with nonsteroidal
anti-inflammatory drugs (NSAIDs) may cause kidney problems. Taking CANASA with azathioprine or
6-mercaptopurine may cause blood problems. Ask your healthcare provider if you are not sure if you are taking
one of these medicines. Your doctor may do certain tests during treatment with CANASA.
What are the possible side effects of CANASA?
CANASA may cause serious side effects, including:
Your healthcare provider will do certain tests before you start using CANASA and during your
Acute Intolerance Syndrome and Other Allergic Reactions.
Some people who use CANASA can have allergic-type reactions, including acute
intolerance syndrome. Other allergic reactions can cause heart problems, including an inflammation
of the sac around the heart (pericarditis), blood problems, and problems with other organs in
the body, including the kidneys, liver, and lungs. When this happens, it is usually in people who
have had an allergic reaction to sulfasalazine. Stop using CANASA and tell your healthcare provider right away if
you get any of these symptoms: cramps, stomach (abdominal) pain, bloody diarrhea, chest pain, a decrease
in the amount of your urine, fever, headache, rash, shortness of breath, eye inflammation, or fatigue.
This can happen in people who have a history of liver problems and have taken other
medicines that contain mesalamine. Tell your healthcare provider right away if you get any of
these symptoms while using CANASA: yellowing of your eyes, itchy skin, feeling very
tired, flu-like symptoms, nausea, or vomiting.
Serious Skin Reactions. Some people who use CANASA can have severe skin reactions. Stop using CANASA
and tell your healthcare provider right away if you develop any of the following signs or symptoms of a severe skin reaction,
including blisters or peeling of your skin, mouth sores, blisters on your lips or around your mouth or eyes, high fever or
flu-like symptoms, enlarged lymph nodes, or skin rash.
CANASA can make your skin sensitive to the sun if you have skin conditions such
as atopic dermatitis and atopic eczema. Try to limit your time in the sun. You should use
sunscreen and wear a hat and clothes that cover your skin if you have to be in the sunlight.
Drink plenty of fluids when using CANASA to decrease your chance of getting
kidney stones. Call your healthcare provider right away if you get any of these symptoms: severe pain in your
side or your back or blood in your urine.
The most common side effects of CANASA include: dizziness, acne, inflammation of
the large intestine (colitis), rectal pain, fever, and rash.
Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not
all the possible side effects of CANASA.
You are encouraged to report negative side effects of prescription drugs to the FDA.
Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help.
Visit AbbVie.com/myAbbVieAssist to learn more.
What is CANASA?
CANASA® (mesalamine) 1000 mg rectal suppository is a prescription medicine used to treat adults
with active ulcerative proctitis (ulcerative rectal colitis).
It is not known if CANASA is safe and effective in children.
Please also see the
full Prescribing Information.
CANASA® and its design are trademarks of Aptalis Pharma Canada ULC, an AbbVie company.
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The product information provided in this site is intended only for residents of the United States. The products discussed on this site may have different product labeling outside of the United States.
The health information described in this site is provided for educational purposes only and is not intended to substitute for discussions with a healthcare provider.